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Author: Admin | 2025-04-28
Of parathyroid hormone. This leads to high calcium levels and low phosphorus levels in your blood. Primary hyperparathyroidism usually occurs randomly. But some people inherit a gene that causes the disorder.Secondary hyperparathyroidismSecondary hyperparathyroidism is the result of another condition that lowers the blood calcium, which then affects the gland's function. This causes your parathyroid glands to overwork and produce high amounts of parathyroid hormone to maintain or restore the calcium level to the standard range. Factors that may result in secondary hyperparathyroidism include: Severe calcium deficiency. Your body may not get enough calcium from your diet, often because your digestive system doesn't absorb the calcium from food. This is common after intestinal surgery, including weight loss surgery. Severe vitamin D deficiency. Vitamin D helps maintain appropriate calcium levels in the blood. It also helps your digestive system absorb calcium from your food.Your body produces vitamin D when your skin is exposed to sunlight. You also get some vitamin D in food. If you don't get enough vitamin D, then calcium levels may drop. Chronic kidney failure. Your kidneys convert vitamin D into a form that your body can use. If your kidneys work poorly, usable vitamin D may decrease and calcium levels drop. This causes parathyroid hormone levels to go up. Chronic kidney failure is the most common cause of secondary hyperparathyroidism.In some people with long-term secondary hyperparathyroidism, usually from end-stage kidney disease, the parathyroid glands enlarge. They begin to release parathyroid hormone on their own. The hormone level doesn't go down with medical treatment and the blood calcium becomes too high. This is called tertiary hyperparathyroidism, and people with this condition may require surgery to remove parathyroid tissue.Risk factorsYou may be at an increased risk of primary hyperparathyroidism if you: Are a woman who has gone through menopause Have had prolonged, severe calcium or vitamin D deficiency Have a rare, inherited disorder, such as multiple endocrine neoplasia, type 1, which usually affects multiple glands Have had radiation treatment for cancer that has exposed your neck to radiation Have taken lithium, a drug most often used to treat bipolar disorderComplicationsComplications of hyperparathyroidism are mainly related to the long-term effect of too little calcium in your bones and too much calcium in your bloodstream. Common complications include: Osteoporosis. The loss of calcium from bones often results in weak, brittle bones that break easily (osteoporosis). Kidney stones. Too much calcium in your
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