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Author: Admin | 2025-04-28
Dosage FormsExcipient information presented when available (limited, particularly for generics); consult specific product labeling.Solution, Oral:Citroma: 1.745 g/30 mL (296 mL) [contains polyethylene glycol, saccharin sodium; lemon flavor]Citroma: 1.745 g/30 mL (296 mL) [low sodium; contains alcohol, usp, benzoic acid, disodium edta]Citroma: 1.745 g/30 mL (296 mL) [low sodium; contains fd&c red #40, saccharin sodium; cherry flavor]Citroma: 1.745 g/30 mL (296 mL) [low sodium; contains saccharin sodium; lemon flavor]GoodSense Magnesium Citrate: 1.745 g/30 mL (296 mL) [contains polyethylene glycol, saccharin sodium]GoodSense Magnesium Citrate: 1.745 g/30 mL (296 mL) [low sodium; contains alcohol, usp, fd&c red #40, saccharin sodium]GoodSense Magnesium Citrate: 1.745 g/30 mL (296 mL) [low sodium; contains saccharin sodium; lemon flavor]GoodSense Magnesium Citrate: 1.745 g/30 mL (296 mL) [saccharin free; contains benzoic acid, disodium edta]Generic: 1.745 g/30 mL (296 mL)Tablet, Oral:Generic: 100 mg PharmacologyMechanism of ActionPromotes bowel evacuation by causing osmotic retention of fluid which distends the colon with increased peristaltic activity Pharmacokinetics/PharmacodynamicsAbsorptionOral: Up to 30%ExcretionUrine (IOM 1997); feces (as unabsorbed drug)Onset of ActionLaxative effect: Oral solution: 0.5 to 6 hours Use: Labeled IndicationsOccasional constipation: Treatment of occasional constipation Use: Off LabelBowel preparation before colonoscopycyesBased on the the American Society for Gastrointestinal and Endoscopy (ASGE) guideline for bowel preparation before colonoscopy, routine use of magnesium citrate as a stand-alone colonoscopy preparation is not recommended for routine use due to limited efficacy data and potential toxicity. A randomized, prospective 2-part study supports use of magnesium citrate as an effective and well tolerated low-volume colonoscopy preparation Berkelhammer 2002. ContraindicationsOTC labeling: When used for self-medication, do not use if on low salt diet Dosage and AdministrationDosing: AdultBowel preparation before colonoscopy (off-label use): Note: This preparation should be avoided in patients with renal impairment, heart failure, decompensated cirrhosis, or baseline electrolyte abnormalities (A-Rahim 2018). There is no standard dosing for administration; the following recommendations
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