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Author: Admin | 2025-04-28
Worsen blood sugar control in people with diabetes. May trigger an angle-closure attack in people with glaucoma. May not be suitable for people with a history of seizures. May interact with several other drugs including those metabolized by cytochrome p450 2D6 or 1A2 enzymes (such as nortriptyline or flecainide). Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects 4. Bottom Line Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. 5. Tips May be taken with or without food. Cymbalta is a delayed-release product. Swallow Cymbalta capsules whole, do not crush or chew. Do not open the capsule and sprinkle on foods or liquids, because this may affect the way the contents of the capsule are absorbed. Dosages of 30 mg/day for at least one week may be desirable initially to improve tolerance to the effects of Cymbalta. There is no evidence that dosages greater than 60mg/day offer any additional benefit. Cymbalta may make you feel dizzy when going from a sitting or lying position to standing. Get up slowly. Report to your doctor any signs of worsening depression or suicidal thoughts particularly during the first few months of therapy. Also report any symptoms such as agitation, hallucinations, a fast heart rate, dizziness, flushing, muscle tremor or rigidity, nausea, vomiting, or diarrhea. Do not stop suddenly as withdrawal or discontinuation symptoms may occur. Taper off slowly on a doctor's advice. Do not drive or operate machinery if this medicine makes you drowsy or impairs your judgment. Avoid alcohol. Report any problems with bleeding or bruising to your doctor. Also, report any unexplained skin changes (such as blisters or rashes), problems with urination, eye pain or swelling, and vision changes. 6. Response and effectiveness May take up to two hours before absorption occurs. Peak concentrations are reached approximately six hours after a dose. Full clinical effects (including relief from depression, anxiety, or pain) may not occur for several weeks.For some conditions (such as diabetic peripheral neuropathy), 60mg of Cymbalta is as effective as 120mg, with fewer side effects.Generally, dosages greater than 60mg a day are associated with more side effects. 7. Interactions Medicines that interact with Cymbalta may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Cymbalta. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak
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