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Author: Admin | 2025-04-28
Rifampin - decreases Ketamine levels- St John’s Wort - decreases Ketamine levels- Ketoconazole - increases Ketamine levels- Cimetidine (Tagamet) - may theoretically increase Ketamine levels- Grapefruit Juice - increases oral Ketamine levelsFor oral forms of Ketamine, such as troches (lozenges), these interactions are particularly significant due to high rates of liver metabolism. Increasing Ketamine levels through medication interactions isn't necessarily beneficial, as it may also elevate the risk of side effects from both Ketamine and the interacting medication, and Ketamine has a specific dose range in which it is effective for the treatment of mood disorders. ConclusionThe medications discussed are just a sample of those identified in peer-reviewed research to potentially interact with Ketamine therapy. Many other medications may also impact Ketamine therapy based on clinical observations, but conclusive scientific evidence may still be pending.Patients are urged to always consult with their prescribing doctor before making changes to their medications, as abrupt alterations can be hazardous. This article aims to inform, not to replace medical advice. Ketamine is a part of a comprehensive treatment plan for mental health and/or chronic pain relief. For optimal outcomes, collaboration between the patient, doctor, therapist, and ketamine provider is essential.We will go over your medications in intake and advise if any medication may need to be held on the day of infusion. Ketamine is a medication that has very few interactions but it is critical to ensure prior to getting started to started with treatment. ReferencesAlbott, C. S., Shiroma, P. R., et al. (2017).
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