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Author: Admin | 2025-04-28
Taking Ambien, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions.If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.The chart below lists drugs that may interact with Ambien. Keep in mind that this chart does not include all drugs that may interact with Ambien. For more information about some of these interactions, see the “Drug interactions explained” section below.Learn more about certain drug interactions that can occur with Ambien.Interaction with selective serotonin reuptake inhibitorsAmbien can interact with a group of drugs called selective serotonin reuptake inhibitors (SSRIs), which are used to treat certain mood conditions such as depression. Taking an SSRI with Ambien can raise your risk of side effects from Ambien.Interaction with CYP3A4 inducersBefore starting Ambien, talk with your doctor about all other drugs you take. They can help determine if one of your medications is a CYP3A4 inducer, and if it may interact with Ambien.Interaction with benzodiazepinesBenzodiazepines may interact with Ambien. You may have a higher risk of side effects from both Ambien and your benzodiazepine if you take these drugs together.Ambien may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests. See below for details.Does Ambien interact with supplements, herbs, or vitamins?Before you start taking Ambien, talk with your doctor and pharmacist about any supplements, herbs, and vitamins you take. Sharing this information with them may help you avoid possible interactions.Ambien interactions with supplementsAmbien interacts with the supplement melatonin, which can also be used to aid sleep. Melatonin and Ambien can both cause drowsiness. So, taking them together may make you too drowsy and increase your risk of serious side effects. Your doctor will likely recommend that you avoid taking melatonin while you’re taking Ambien.If you have questions about interactions that may affect you, talk with your doctor or pharmacist.Ambien interactions with herbsValerian and Ambien can both cause drowsiness. So, taking them together may make you too drowsy and increase your risk of serious side effects.St. John’s Wort is a CYP3A4 inducer. CYP3A4 is an enzyme that is responsible for breaking down Ambien. CYP3A4 inducers cause this enzyme to work faster than usual. This may make Ambien less effective.Taking valerian or St. John’s Wort with Ambien is not usually recommended. If you take one of these supplements, talk with your doctor about your options.Ambien and vitaminsThere are currently no reports of Ambien interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future.For this reason, it’s still important to check with your doctor or pharmacist before using any of these products while taking Ambien.Does Ambien interact with food?No, there are currently no reports of Ambien interacting with food. If you have questions about eating certain foods during your treatment with Ambien, talk with your doctor.Does Ambien interact with vaccines?There haven’t been any interactions reported between Ambien and vaccines. If you have questions about getting
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