Metronidazole cns signs

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Actual: Mechanism of Action. The activity of metronidazole is specific for anaerobic bacteria and protozoa. 28 It is specific particularly for Giardia organisms. Metronidazole disrupts DNA in target microbes through reaction with intracellular metabolites. Clinical Signs. The most severe side effect of metronidazole is dose-related CNS toxicity.
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Monitor and report signs of CNS toxicity, including irritability and sleep loss. Sustained or severe CNS signs are typically consistent with hyperthyroidism and

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by A Agent 2024observed carefully for signs and symptoms of CNS depression, and the dose of gabapentin or Signs of overdose may include: dizziness

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HydrOXYzine: May enhance the CNS depressant effect of CNS Depressants. together with hydroxyzine. Increase monitoring of signs/symptoms of CNS

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Overdose with diphenhydramine can cause symptoms ranging from CNS stimulation to CNS depression. The usual signs of mild overdose are sedation and clumsiness.

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Peritoneal dialysis: Monitor for signs of toxicity due to potential accumulation of metronidazole metabolites Enhanced CNS cardiac toxicity.

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Patients who require concomitant treatment with CNS depressants, including opioids should be carefully observed for signs of CNS depression, such as somnolence

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together with hydroxyzine. Increase monitoring of signs/symptoms of CNS depression in any patient receiving hydroxyzine together with another CNS depressant.

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Patients who require concomitant treatment with CNS depressants, including opioids should be carefully observed for signs of CNS depression, such as somnolence

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CNS toxicity). Superinfections and promotion of Additive: Aminophylline, clindamycin, linezolid, theophylline, metronidazole (at metronidazole

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