MHRA advises monitor. Severity: Severe. Evidence: Anecdotal. Metoprolol. Bupropion is predicted to increase the exposure to Metoprolol. Manufacturer makes no
bupropion therapy: a probable drug-drug interaction with metoprolol. Moody DE, Backman RL: Metoprolol and bupropion interaction: a case study.
Metoprolol is available as the active drug metoprolol tartrate in Antidepressants like bupropion (Wellbutrin, Zyban), fluoxetine
Bupropion moderately inhibits the liver enzyme metabolizing Metoprolol. That means, that a lower dose of Metoprolol will have a stronger and longer effect.
Metoprolol: CYP2D6 Inhibitors (Strong) may increase the serum concentration of Metoprolol. Bupropion sandoz
The metabolism of Metoprolol can be decreased when combined with Bupropion. bupropion HCl: from bupropion to bupropion SR to bupropion XL. Prim Care
Metoprolol. Bupropion, The metabolism of Metoprolol can be decreased when combined with Bupropion. Buspirone, The metabolism of Buspirone can be decreased
May lower seizure threshold; keep bupropion dose as low as possible. metoprolol. bupropion will increase the level or effect of metoprolol by affecting hepatic
Mental health medications: bupropion (brand name Wellbutrin; see metoprolol (metoprolol succinate). Alcohol speeds up the action of
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