Dox drugs

Doxorubicin (DOX), also known as adriamycin, is a DNA topoisomerase II inhibitor and belongs to the family of anthracycline anticancer drugs. DOX is used for the treatment of a wide variety of cancer types. However, resistance among cancer cells has emerged as a major barrier to effective treatment using DOX.

Pronunciation: dox-il-a-meen peer-ih-dox-een. To hear audio pronunciation of this topic, purchase a subscription or log in. Trade Name(s). Bonjesta

Background Free doxorubicin (Dox) is used as a chemotherapeutic agent against hepatocellular carcinoma (HCC), but it results in cardiotoxicty as a major side effect. Hence, a controlled Dox drug delivery system is extremely demanded. Methods Dox was loaded into the non-toxic biodegradable polycaprolactone (PCL) nanocapsules using the double emulsion method. Characterization of Dox-PCL

Our results show that DOX and sildenafil induce a potent antitumor effect in prostate cancer while simultaneously providing a cardioprotective effect. Sildenafil Potentiates DOX-Induced Killing

Many chemotherapy drugs such as DOX can induce cancer cells to express more PD-L1 15,38,39. Indeed, after treating with DOX or PLD

by S Al-Nadaf 2024 Cited by 20An alternative treatment option is the use of DOX, the most effective drug, in combination with prednisone. Prior studies with single-agent DOX

Moreover, it has been demonstrated that the formation of DOX DNA adducts can activate the DNA damage response (DDR) pathway independently of the effect of the drug on topoisomerase II. Importantly, DOX DNA adducts can be detected at drug doses that are appropriate to clinical practice, which suggests that DOX DNA adducts can be formed

Because tertiary tricyclic antidepressants such as amitriptyline, imipramine, and dox-.

DOX is an anthracycline antibiotic, and it is one of the most frequently used chemotherapy drugs for treating breast cancer. DOX leads to apoptosis by initiating death-signaling pathways in target