Elimination of drugs

All drugs are eventually eliminated from the body. They may be eliminated after being chemically altered (metabolized), or they may be eliminated intact. Most drugs, particularly water-soluble drugs and their metabolites, are eliminated largely by the kidneys in urine. Therefore, drug dosing depends largely on kidney function.

Both of these drugs are eliminated from the body by the kidneys. Because they are both eliminated in the same way, the drugs will compete to be

Elimination and Excretion Elimination is the removal of drug from the plasma, and includes distribution and metabolism Excretion is the

the effect of reduced renal function on drugs that are primarily hepatically eliminated and the For renally eliminated drugs, the half-life of

What are the drug interactions of Flomax and Viagra? The elimination of Flomax from the body may be reduced by: other drugs that reduce the elimination of drugs by liver enzymes. Reduced elimination may lead to increased side effects of Flomax.

The elimination of some benzodiazepines (for example, alprazolam [Xanax] and diazepam [Valium]) is reduced by drugs that slow the elimination of drugs in the

Ke (Elimination Rate) - Half-Life Ke, the elimination rate constant can be defined as the fraction of drug in an animal that is eliminated per

half of the drug to be eliminated from the body. The shorter the half-life, the quicker the drug is eliminated. In combination with

Naproxen has an elimination half life of 12 to 17 hours. It takes approximately 5.5 x elimination half-life for a drug to be eliminated from