Drugs that increase uric acid
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increase urinary excretion of uric acid used as second-line drugs in patients who are under-excretors of uric acid and in those resistant to or
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Uricosuric medications (drugs) are substances that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in blood
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The PharmGKB Uric Acid-Lowering Drugs Pathway, PD covers drugs that either inhibit formation of uric acid or act directly upon uric acid to increase secretion.
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Diuretics are one of the most important causes of secondary hyperuricaemia. Drugs raise serum uric acid level by an increase of uric acid reabsorption and/or decrease in uric acid secretion. Several drugs may also increase uric acid production.
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lower the production of uric acid, such as allopurinol; increase the amount of uric acid output in urine, such as probenecid; break down uric acid, such as pegloticase
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33. URICOSURICS/ Increasing uric acid excretion Uricosuric drugs are organic acids that inhibit the reabsorption of uric acid by inhibiting
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Pyrazinamide and Ethambutol are antitubercular drugs that raise Uric acid levels by lowering excretion and increasing uric acid reabsorption and cause life-
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by C Ben Salem 2024 Cited by 241Drugs raise serum uric acid level by an increase of uric acid reabsorption and/or decrease in uric acid secretion. Several drugs may also increase uric acid
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However, the rats responded well to uricosuric drugs and diuretics. Probenecid and uricosuric diuretics such as tienilic acid induced hyperuricosuria due to the increase of fractional excretion of uric acid and/or the increase of the filtered amount of uric acid with the rise of plasma uric acid.
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