2.1 The substitution of levothyroxine Sodium Injection to oral levothyroxine with the use of IV levothyroxine is being substituted for oral
IV: Note: The relative bioavailability of injectable and oral levothyroxine oral to IV as accurate dosing conversions have not been established. IV dose
by CF James 2024Introduction: Hypothyroid patients with failure to take/absorb oral levothyroxine might require intravenous levothyroxine. IV levothyroxine is
The IV dose should be reduced to 70% or less of the usual oral dose. For example, if a patient was receiving 100 micrograms of oral levothyroxine the dose of IV levothyroxine would be 70 micrograms.
Since oral absorption of levothyroxine is incomplete, the IV dosage should be reduced to 50 to 80% of the previously established oral dosage of levothyroxine.
safe. The conversion of the IV levothyroxine dose to an oral dose has been already discussed in Section 5 of this memorandum. It should be also recognized that transition from IV levothyroxine to oral administration during the treatment of myxedema coma is different from converting an oral levothyroxine product to
When switching from IV to oral liothyronine therapy, discontinue IV liothyronine, then initiate oral liothyronine at low dosage and increase gradually according to patient s response. When switching from IV liothyronine to oral levothyroxine therapy, consider delay (several days) in onset of activity of levothyroxine and discontinue IV
The IV dose should be reduced to 70% or less of the usual oral dose. For example, if a patient was receiving 100 micrograms of oral levothyroxine the dose of IV levothyroxine would be 70 micrograms. See table below for suggested dose conversions for ease of administration. Oral levothyroxine dose IV levothyroxine dose 50 micrograms 35 micrograms
The IV dose should be reduced to 70% or less of the usual oral dose. For example, if a patient was receiving 100 micrograms of oral levothyroxine the dose of IV levothyroxine would be 70 micrograms. See table below for suggested dose conversions for ease of administration. Oral levothyroxine dose IV levothyroxine dose 50 micrograms 35 micrograms
As it tends to happen in the telling of oral history, Rufus' ancestors' true story got altered over time. Sixtus IV put the guard dogs in place to assure the priests stayed true to him. Michelangelo was gay after all!