Fenofibrate is an alternative to gemfibrozil for the treatment of high triglycerides. Fenofibrate can also be used to lower total cholesterol. Fenofibrate
In the United States, gemfibrozil, fenofibrate, and fenofibric acid are the only fibrates approved for clinical use. Both statins and fibrates
fenofibrate (64%) compared to gemfibrozil (39%; P 0.0005). The study demonstrated that patients switched from gemfibrozil to fenofibrate due
In contrast, two very small trials have compared gemfibrozil vs. fenofibrate and reported that fenofibrate was more efficacious in lowering LDL levels than gemfibrozil (159,160). In very rare instances fibrates can cause a paradoxical marked decrease in HDL-C levels ( ).
Gemfibrozil (Lopid) Fenofibrate (Antara, Lofibra, Tricor, and Triglide) Fenofibric Acid (Fibricor and Trilipix)
other cholesterol lowering medicine - gemfibrozil, niacin, fenofibrate, fenofibric acid, and others; colchicine; antibiotic or antifungal
Gemfibrozil (Lopid) and fenofibrate (TriCor) appear equally safe and effective. Fenofibrate is more convenient, since it is taken once
When statin-fibrate combination therapy is indicated, fenofibrate or fenofibric acid is preferred because of a reduced incidence of DDIs compared with the gemfibrozil-statin combination. There are circumstances in which gemfibrozil may be the only available fibrate, cost may be a consideration, or fenofibrate may not be tolerated.
statins. Gemfibrozil is reported to cause a moderate increase in the area gemfibrozil and fenofibrate on the single-dose pharmacokinetics of atorvastatin.
then vs than
accept vs expect
alright vs all right
its vs it's
there vs their
waist vs waste
your vs you're, you are