Gemfibrozil vs fenofibrate

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Actual: When the coadministration of statins and fibrates is needed, fenofibrate or fenofibric acid is preferred over gemfibrozil, but if gemfibrozil
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Fenofibrate is an alternative to gemfibrozil for the treatment of high triglycerides. Fenofibrate can also be used to lower total cholesterol. Fenofibrate

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In the United States, gemfibrozil, fenofibrate, and fenofibric acid are the only fibrates approved for clinical use. Both statins and fibrates

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fenofibrate (64%) compared to gemfibrozil (39%; P 0.0005). The study demonstrated that patients switched from gemfibrozil to fenofibrate due

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In contrast, two very small trials have compared gemfibrozil vs. fenofibrate and reported that fenofibrate was more efficacious in lowering LDL levels than gemfibrozil (159,160). In very rare instances fibrates can cause a paradoxical marked decrease in HDL-C levels ( ).

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Gemfibrozil (Lopid) Fenofibrate (Antara, Lofibra, Tricor, and Triglide) Fenofibric Acid (Fibricor and Trilipix)

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other cholesterol lowering medicine - gemfibrozil, niacin, fenofibrate, fenofibric acid, and others; colchicine; antibiotic or antifungal

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Gemfibrozil (Lopid) and fenofibrate (TriCor) appear equally safe and effective. Fenofibrate is more convenient, since it is taken once

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When statin-fibrate combination therapy is indicated, fenofibrate or fenofibric acid is preferred because of a reduced incidence of DDIs compared with the gemfibrozil-statin combination. There are circumstances in which gemfibrozil may be the only available fibrate, cost may be a consideration, or fenofibrate may not be tolerated.

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statins. Gemfibrozil is reported to cause a moderate increase in the area gemfibrozil and fenofibrate on the single-dose pharmacokinetics of atorvastatin.

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