Insti drugs

☑️@insti_drugs · 7930 subscribers · Content 18+ 🔞
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Actual: Methods. To characterize the suitability of the INSTI-resistance mutations for transmitted HIV-1 drug resistance (TDR) surveillance, we classified them according to their presence on published expert lists, conservation in INSTI-naive persons, frequency in INSTI-treated persons and contribution to reduced in vitro susceptibility.
4.7 rating 2025-04-26
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by S Aquaro 2024 Cited by 32Also, Integrase strand transfer inhibitors (INSTIs) are the class of ARV drugs most recently approved by the FDA for the treatment of HIV-1 infections. INSTIs

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by C Muccini 2024 Cited by 4INSTI drug and to the INSTI drug class. DR within the INSTI class was defined by the presence of at least low-level resistance to ≥1 drug

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by M Li 2024 Cited by 22drugs, the IN strand transfer inhibitors (INSTIs). Collectively, these changes weaken chelation of the bound INSTI, leading to a reduction in

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by BN Harding 2024 Cited by 7These findings suggest INSTI use may increase the risk of anaemia. If confirmed, screening for anaemia development in users of INSTIs may be beneficial.

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Dolutegravir-lamivudine (Dovato, ViiV), INSTI/NRTI, Bictegravir-emtricitabine-TAF (Biktarvy, Gilead), INSTI/NRTI, .

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Recommended ART regimens for treatment-naive patients with HIV infection are INSTI-based, and are as follows: drugs - darunavir

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The newest class of antiretrovirals for all persons living with HIV are the integrase strand transfer inhibitors (INSTIs). Since 2024, five INSTIs have been introduced: raltegravir, elvitegravir, dolutegravir, bictegravir, and cabotegravir. The INSTIs have favorable pharmacokinetic and pharmacodynam

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The newest class of antiretrovirals for all persons living with HIV are the integrase strand transfer inhibitors (INSTIs). Since 2024, five INSTIs have been introduced: raltegravir, elvitegravir, dolutegravir, bictegravir, and cabotegravir. The INSTIs have favorable pharmacokinetic and pharmacodynamic properties, which contribute to both their effectiveness and their ease of use. With the

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by C Spitznagel 2024well as individual INSTI drugs. We compared the proportion of women with viral suppression at delivery between INSTIs and non-INSTIs as well between

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